发现否认阿尔茨海默氏病的新认知标记
作者:365bet登录日期:2025/04/02 浏览:
Science and Technology Daily, Beijing, April 1 (Reporter Zhang Menganran) The Journal Nature Medicine reported on March 31 that a potential new Biomarker predicts the future recovery of providing and falling patients with early Alzheimer's patients.该蛋白质指标可以提高预测阿尔茨海默氏病症状和发育的能力。 Alzheimer's disease is the most common form of dementia, and the complex pathological processes involved occur decades earlier than clinical symptoms. Decline cognitive refers to the gradual loss of mental ability, which is rapid and slow in Alzheimer's disease, and symptoms usually occur between the ages of 40 and 100. It usually takes 2-20 years to develop from mild dementia. Although the psAdvancement is made in the discovery of biomarkers of early Alzheimer's disease (such as amyloid beta and tau proteins), these indicators do not fully explain the differences of disability of the provisional observed in patients患阿尔茨海默氏病。斯坦福大学团队对美国六个独立人群,瑞典和芬兰进行了大规模审查。脑脊液是指包围大脑和脊柱的液体。然后将分析的结果与数据,认知功能,年龄,性别和阿尔茨海默氏病风险基因结合在一起,这些疾病风险基因来自这些主题的脑脊液和脑疮。该小组发现,脑脊液的特定蛋白质与受损的提供者密切相关,并且这种关系与β-淀粉样蛋白和TAU蛋白无关。二手研究正在研究机器的研究,以表明两个突触蛋白YWHAG和NPTX2的比率可能比当前的金生物标准标准更可靠地表明了赋予无残疾的残疾。该比率(即YWHAG:NPTX2)增加,并且与增加的提供者增加和痴呆症的可能性更高有关。这只老鼠IO将从生活开始时随着年龄的增长而增加,还可以预测阿尔茨海默氏病的发作和发展。新发现为早期发现和监测阿尔茨海默氏病提供了潜在的新生物标志物。该生物标志物还可以找到相关药物治疗的临床试验的更敏感的标记。
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